Wiskott-Aldrich Syndrome Protein Family

Medical Dictionary -> Wiskott-Aldrich Syndrome Protein Family

Search:

Wiskott-Aldrich Syndrome Protein Family

A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.