Waterhouse-Friderichsen Syndrome

Medical Dictionary -> Waterhouse-Friderichsen Syndrome

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Waterhouse-Friderichsen Syndrome

A condition caused by overwhelming BACTERIAL INFECTIONS or SEPTICEMIA, leading to HEMORRHAGE and NECROSIS of the ADRENAL GLAND. It is characterized by rapidly developing ADRENAL INSUFFICIENCY; HYPOTENSION; and widespread cutaneous PURPURA. This syndrome may occur at any age but is more common in children.