Positive Transcriptional Elongation Factor B

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Positive Transcriptional Elongation Factor B


A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including cyclin T1, T2 and K. It functions by phosphorylating the carboxy-terminal domain (CTD) of RNA POLYMERASE II, which results in more processive transcription complexes.

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