Phenylalanine Ammonia-Lyase

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Phenylalanine Ammonia-Lyase


An enzyme that catalyzes the deamination of L-phenylalanine to form trans-cinnamate and ammonia. It may also act on L-tyrosine. Since the enzyme deprives neoplastic tissue of phenylalanine, it has been used experimentally in the treatment of acute lymphoblastic leukemia. The enzyme is obtained from many plants. EC 4.3.1.5.

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