Oncogene Proteins v-erbB

Medical Dictionary -> Oncogene Proteins v-erbB

Oncogene Proteins v-erbB


Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus. The protein is a truncated form of the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) whose kinase domain is constitutively activated by deletion of the ligand-binding domain.


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