DNA Topoisomerases, Type I

Medical Dictionary -> DNA Topoisomerases, Type I

DNA Topoisomerases, Type I


DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.


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