Cyclin-Dependent Kinase 4

Medical Dictionary -> Cyclin-Dependent Kinase 4

Cyclin-Dependent Kinase 4


Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.


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