Core Binding Factor Alpha 2 Subunit

Medical Dictionary -> Core Binding Factor Alpha 2 Subunit

Core Binding Factor Alpha 2 Subunit


A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.


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