Cleavage And Polyadenylation Specificity Factor

Medical Dictionary -> Cleavage And Polyadenylation Specificity Factor

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Cleavage And Polyadenylation Specificity Factor

An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.