Chromosomes, Artificial, Mammalian

Medical Dictionary -> Chromosomes, Artificial, Mammalian

Chromosomes, Artificial, Mammalian


DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful replication, propagation to and maintainance in progeny mammalian cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.


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