Arachidonate 5-Lipoxygenase

Medical Dictionary -> Arachidonate 5-Lipoxygenase

Arachidonate 5-Lipoxygenase


An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes. EC 1.13.11.34.


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