Acidosis, Renal Tubular

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Acidosis, Renal Tubular

A rare sometimes familial disorder of the renal tubule characterized by the inability to excrete urine of normal acidity. This leads to a hyperchloremic acidosis which is often associated with one or more secondary complications such as hypercalcinuria with nephrolithiasis and nephrocalcinosis, rickets, or osteomalacia and severe potassium depletion.